Optune®

NEW DEVICE PROVIDES HELP FOR GLIOBLASTOMA TUMORS.

Optune

Optune® is a noninvasive device to treat newly-diagnosed and recurrent Glioblastoma (GBM) Tumors. The device is a wearable, portable, FDA-approved device indicated to treat GBM tumors in adult patients 22 years of age or older.

 

If you have newly diagnosed GBM, Optune is used together with a chemotherapy called temozolomide (TMZ) if:

  • Your cancer is confirmed by your healthcare professional AND
  • You have had surgery to remove as much of the tumor as possible

 

If your tumor has come back, Optune can be used alone as an alternative to standard medical therapy if:

  • You tried surgery and radiation and they did not work or are no longer working AND
  • You have tried chemotherapy and your GBM has been confirmed by your healthcare professional

 

Optune works by delivering low-intensity, wave-like electric fields to the location of the GBM tumor. These electric fields interfere with GBM tumor cell division, which may slow down or stop cell division and may cause the cells to be destroyed.

 

If you would like more information about Optune, please visit their official website.

Are You A Candidate?

Optune is not for everyone. You may not be a candidate for Optune if you have:

  • An implanted medical device (programmable shunt), skull defect (missing bone with no replacement), or bullet fragment. Optune has not been tested in people with implanted electronic devices, which may cause the devices not to work properly, and Optune has not been tested in people with skull defects or bullet fragments, which may cause Optune not to work properly.
  •  A known sensitivity to conductive hydrogels (the gel on the arrays placed on the scalp like the ones used on EKGs). When Optune comes into contact with the skin, it may cause more redness and itching or may rarely cause a life-threatening allergic reaction.

 

Do not use Optune if you are pregnant or are planning to become pregnant. It is not known if Optune is safe or effective during pregnancy.

Cautions

  • Optune should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune.
  • Do not use any parts that did not come with the Optune Treatment Kit sent to you by Novocure or given to you by your doctor.
  • Do not get the device or transducer arrays wet.
  • If you have an underlying serious skin condition where the transducer arrays are placed, discuss with your doctor whether this may prevent or temporarily interfere with Optune treatment.

Side Effects

  • The most common side effects of Optune when used together with chemotherapy (temozolomide, or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression.
  • The most common side effects when using Optune alone were scalp irritation (redness and itchiness) and headache. Other side effects were malaise, muscle twitching, fall and skin ulcers.

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Anterior Cervical Fusions

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Dr. John M. Abrahams will be discussing Anterior Cervical Fusions